location /{// …..省略部分代码    

if(!-e $request_filename){    

rewrite  ^(.*)$  

/index.php?s=$1  last;    

break;}}

location /youdomain/{    

if(!-e $request_filename){    

rewrite  ^/youdomain/(.*)$  

/youdomain/index.php?s=$1  

last;}}